I have many favorite vacation memories...
The stand out is sort of bitter sweet. About five years ago, I took my parents with my daughter to WDW. My mother getting around with a scooter, but was at the time able to get on and off it and actually enjoy the trip. Her favorite ride was Mission Space (the non-spin version.) I have wonderful pictures as it was mid-December and we looked at all the Christmas displays. My mother is no longer able to travel. This ended up being her "last vacation." She still talks about how much fun she had and continues to encourage our trips to the World.